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Silica Magnetic Beads is Fe3O4 magnetic beads coated with a silicon dioxide (SiO2) layer. Since silica is able to bind to the nucleic acids, Silica Magnetic Beads serves as simple and efficient tool for plasmid DNA purification for transfection or sequencing applications, genomic DNA purification for research or clinical applications, RNA purification for qPCR analysis, or PCR product clean-up for downstream analysis.
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| Application | High adsorption & easy suspension |
| Characteristic of 1 mL | Suspension more than 2 min after mixing. | Core | Iron Oxide (Fe3O4) | Layer | Silica (SiO2) |
| Concentration | 50 mg/mL |
| Mean Diameter of Particles | 2.5 ~ 4.5 μm |
| Solution | ddH2O |
| Capacity | > 4 mg DNA/mL |
The application of Beads-Silica is relative characteristic of Algent Beads series that is all sedimentation particles. Difference brand will be different.
MBXE00006：The appearance of supernatant may black or dark brown color that is normal at a standstill due to high suspension of product characteristic, please feel free to use.
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• Binding Buffer, pH 8.0:
- 4 M Guanidinium thiocyanate
- 40 mM Tris
- 17.6 mM EDTA
• Wash Buffer, pH 8.0:
- 10 mM Tris-HCl buffer
- 1 mM EDTA
- 70% EtOH
• Elution Buffer, pH 8.0:
- 10 mM Tris-HCl
- 1 mM EDTA