Anti-ZO-1 tight junction protein Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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TJP1
Host
Storage
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Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/2000 IHC: 1/100-1/500
Immunogen
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KLH conjugated synthetic peptide derived from human ZO-1
Molecular Weight
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Calculated MW: 195 kDa; Observed MW: 250 kDa
Formulation
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0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Form
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Liquid
Gene ID
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7082
Uniprot ID
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Q07157
Background
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This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene. The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions.
Research Area
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Tags & Cell Markers
Synonyms
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TJP1; ZO-1; tight junction protein 1;Tight junction protein ZO-1;Zona occludens protein 1;Zonula occludens protein 1