Anti-ZFYVE27 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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ZFYVE27
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Fusion protein of human ZFYVE27
Molecular Weight
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Calculated MW: 46 kDa; Observed MW: 46 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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118813
Uniprot ID
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Q5T4F4
Background
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This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear.
Research Area
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-
Synonyms
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zinc finger FYVE-type containing 27; SPG33; PROTRUDIN