Anti-YY1 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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YY1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Immunogen
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A synthesized peptide derived from human YY1
Molecular Weight
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Calculated MW: 45 kDa; Observed MW: 68 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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7528
Uniprot ID
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P25490
Background
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Its activity is regulated by transcription factors and cytoplasmic proteins that have been shown to abrogate or completely inhibit YY1-mediated activation or repression. For example, it acts as a repressor in absence of adenovirus E1A protein but as an activator in its presence. Acts synergistically with the SMAD1 and SMAD4 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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YY1; Delta transcription factor; INO80 complex subunit S; NF-E1; Yin and yang 1; YY-1