Anti-YY1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
YY1
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R01-1D3
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IP: 1/20
Immunogen
-
A synthetic peptide of human YY1
Molecular Weight
-
Calculated MW: 45 kDa; Observed MW: 65 kDa
Formulation
-
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
-
Liquid
Gene ID
-
7528
Uniprot ID
-
P25490
Background
-
Its activity is regulated by transcription factors and cytoplasmic proteins that have been shown to abrogate or completely inhibit YY1-mediated activation or repression. For example, it acts as a repressor in absence of adenovirus E1A protein but as an activator in its presence. Acts synergistically with the SMAD1 and SMAD4 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
Research Area
-
Epigenetics and Nuclear Signaling
Synonyms
-
YY1; Delta transcription factor; INO80 complex subunit S; NF-E1; Yin and yang 1; YY-1