Anti-XRCC1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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XRCC1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R05-7K6
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Immunogen
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A synthesized peptide derived from human XRCC1
Molecular Weight
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Calculated MW: 69 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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7515
Uniprot ID
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P18887
Background
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XRCC1 acts as a scaffold protein to coordinate DNA abasic site repair through interaction with several other repair proteins. At least eight XRCC1 protein partners have been identified, including the polynucleotide kinase PNK, DNA ligase III, poly (ADP-ribose) polymerase, and PCNA.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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XRCC1; DNA repair protein XRCC1; X-ray repair cross-complementing protein 1