Anti-XRCC1 (3F6) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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XRCC1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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3F6-G7-F7
Isotype
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IgG1
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Purified recombinant human XRCC1 protein fragments expressed in E.coli.
Molecular Weight
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Calculated MW: 69 kDa; Observed MW: 82 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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7515
Uniprot ID
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P18887
Background
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XRCC1 acts as a scaffold protein to coordinate DNA abasic site repair through interaction with several other repair proteins. At least eight XRCC1 protein partners have been identified, including the polynucleotide kinase PNK, DNA ligase III, poly (ADP-ribose) polymerase, and PCNA.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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XRCC1; DNA repair protein XRCC1; X-ray repair cross-complementing protein 1