Anti-XIAP Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
-
XIAP
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
-
Synthetic peptide of human XIAP
Molecular Weight
-
Calculated MW: 57 kDa; Observed MW: 57 kDa
Formulation
-
pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
-
Liquid
Gene ID
-
331
Uniprot ID
-
P98170
Background
-
This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme.
Research Area
-
Cell Biology
Synonyms
-
API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3