Anti-XBP1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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XBP1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R03-6B2
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human XBP1
Molecular Weight
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Calculated MW: 29 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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7494
Uniprot ID
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P17861
Background
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Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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XBP1; TREB5; XBP2; X-box-binding protein 1; XBP-1; Tax-responsive element-binding protein 5