Anti-WNK3 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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WNK3
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Synthetic peptide of human WNK3
Molecular Weight
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Calculated MW: 198 kDa; Observed MW: 198 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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65267
Uniprot ID
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Q9BYP7
Background
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This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants.
Research Area
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Signal Transduction
Synonyms
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WNK lysine deficient protein kinase 3; PRKWNK3