Anti-Wilms Tumor Protein Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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WT1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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9D1-8B8-4B8
Isotype
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IgG1
Reactivity
Application
Application Details
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IHC: 1/100-1/500
Immunogen
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Synthesized peptide derived from human Wilms' Tumor 1(WT1)
Molecular Weight
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-
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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7490
Uniprot ID
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P19544
Background
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Has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG.
Research Area
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Tags & Cell Markers
Synonyms
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GUD; AWT1; WAGR; WT33; NPHS4; WIT-2; EWS-WT1