Anti-WDR82 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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WDR82
Host
Storage
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Store at 2-8°C for up to 2 weeks. store at -20°C for long term storage in small aliquots. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/2000 IHC: 1/250
Immunogen
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This WDR82 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide from the N-terminal region of human WDR82.
Molecular Weight
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Calculated MW:35 kDa; Observed MW: 35 kDa
Formulation
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Liquid in PBS containing 0.09% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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80335
Uniprot ID
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Q6UXN9
Background
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Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes. Facilitates histone H3 'Lys-4' methylation via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR2A). Component of PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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WD repeat-containing protein 82, Protein TMEM113, Swd2, WDR82, TMEM113, WDR82A