Anti-WDR5 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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WDR5
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human WDR5
Molecular Weight
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Calculated MW: 37 kDa; Observed MW: 37 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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11091
Uniprot ID
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P61964
Background
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Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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WDR5; BIG3; WD repeat-containing protein 5; BMP2-induced 3-kb gene protein