Anti-VCAM1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
Vcam1
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R07-6E9
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IP: 1/20
Immunogen
-
Recombinant protein of mouse VCAM1
Molecular Weight
-
Calculated MW: 81 kDa; Observed MW: 100 kDa
Formulation
-
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
-
Liquid
Gene ID
-
22329
Uniprot ID
-
P29533
Background
-
Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
Research Area
-
Signal Transduction
Synonyms
-
VCAM1; L1CAM; VCAM 1; V CAM 1; DKFZp779G2333; CD106