Anti-VAT2 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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SLC18A2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Synthetic peptide of human SLC18A2
Molecular Weight
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Calculated MW: 56 kDa; Observed MW: 56 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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6571
Uniprot ID
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Q05940
Background
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The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine .
Research Area
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Neuroscience
Synonyms
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SVAT; SVMT; VAT2; VMAT2