Anti-VAMP2 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
-
VAMP2
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
Immunogen
-
A synthesized peptide derived from human VAMP2
Molecular Weight
-
Calculated MW: 13 kDa; Observed MW: 16 kDa
Formulation
-
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
-
Liquid
Gene ID
-
6844
Uniprot ID
-
P63027
Background
-
The SNARE complex is involved in vesicular transport and membrane fusion, a process regulated by calcium. In neurons, VAMP2 is predominantly inserted in presynaptic vesicle membranes. Assembly of VAMP2 with the plasma membrane SNAREs syntaxin 1 and SNAP25 is a key event necessary for membrane fusion and neurotransmitter release.
Research Area
-
Signal Transduction
Synonyms
-
vesicle-associated membrane protein 2 (synaptobrevin 2); SYB2; VAMP-2