Anti-USP13 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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USP13
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R08-8D3
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Immunogen
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A synthetic peptide of human USP13
Molecular Weight
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Calculated MW: 97 kDa; Observed MW: 97 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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8975
Uniprot ID
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Q92995
Background
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Mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Also deubiquitinates USP10, an essential regulator of p53/TP53 stability.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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Deubiquitinating enzyme 13; Isopeptidase T3; ISOT3; UBP13; USP13