Anti-ULBP1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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ULBP1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R86-8D-9
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthesized peptide derived from human ULBP1
Molecular Weight
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Calculated MW:28kDa;Observed MW:36kDa
Formulation
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Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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80329
Uniprot ID
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Q9BZM6
Background
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Ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway.
Research Area
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Immunology
Synonyms
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Alcan beta; N2DL1; NKG2DL1; RAET1I; UL16; UL16 binding protein 1; ULBP1;