Anti-Ubiquitin Protein Ligase E3A Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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UBE3A
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R04-8K9
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthesized peptide derived from human UBE3A
Molecular Weight
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Calculated MW: 101 kDa; Observed MW: 101 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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7337
Uniprot ID
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Q05086
Background
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E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the RAD23A and RAD23B, MCM7 (which is involved in DNA replication), annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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Ubiquitin-protein ligase E3A; UBE3A; E6AP; EPVE6AP; HPVE6A