Anti-Ubiquitin Conjugating Enzyme E2 N Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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UBE2N
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R07-8X9
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Immunogen
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A synthesized peptide derived from human Ube2N / Ubc13
Molecular Weight
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Calculated MW: 17 kDa; Observed MW: 17 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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7334
Uniprot ID
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P61088
Background
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The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. This type of polyubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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BLU; HEL-S-71; Ubc13; UbCH ben; UbcH13; UBCHBEN; Ube2n