Anti-Ubiquitin Conjugating Enzyme E2 C Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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UBE2C
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R08-4F5
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Immunogen
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Recombinant protein of human UBE2C
Molecular Weight
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Calculated MW: 20 kDa; Observed MW: 20 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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11065
Uniprot ID
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O00762
Background
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Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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UBCH 10; UbcH10; Ube2c