Anti-Ubiquitin Conjugating Enzyme E2 A/B Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
UBE2A/UBE2B
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R87-4N-5
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IHC: 1/100-1/200 IF: 1/50-1/200
Immunogen
-
A synthesized peptide derived from UBE2B
Molecular Weight
-
Calculated MW: 17 kDa;Observed MW:17kDa
Formulation
-
Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
-
Liquid
Gene ID
-
7319/7320
Uniprot ID
-
P63146
Background
-
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1.
Research Area
-
Epigenetics and Nuclear Signaling
Synonyms
-
hHR6B; HR6B; RAD6B; UBC2; UBE2B;