Anti-U2AF2 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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U2AF2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Fusion protein of human U2AF2
Molecular Weight
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Calculated MW: 54 kDa; Observed MW: 54 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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11338
Uniprot ID
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P26368
Background
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Necessary for the splicing of pre-mRNA. Induces cardiac troponin-T (TNNT2) pre-mRNA exon inclusion in muscle. Regulates the TNNT2 exon 5 inclusion through competition with MBNL1. Binds preferentially to a single-stranded structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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hU2AF65; U2af2; U2AF65