Anti-Trk B Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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NTRK2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R46-3E-2
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/100-1/200 IP: 1/50
Immunogen
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A synthesized peptide derived from human TrkB
Molecular Weight
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Calculated MW: 92 kDa;Observed MW:90,140kDa
Formulation
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Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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4915
Uniprot ID
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P15209
Background
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Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.
Research Area
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Neuroscience
Synonyms
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BDNF tropomyosine receptor kinase B; GP145 TrkB; GP145-TrkB/GP95-TrkB; GP95 TrkB; Neurotrophic receptor tyrosine kinase 2; Ntrk2; RATTRKB1; Tkrb; TRKB; TrkB tyrosine kinase; TRKB1; Tropomyosin related kinase B;