Anti-TriMethyl-Histone H3 (Lys9) Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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H3-4
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ChIP: 1:20 - 1:100
Immunogen
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A synthetic methylated peptide corresponding to residues surrounding K9 of human histone H3
Molecular Weight
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Calculated MW: 16 kDa; Observed MW: 16 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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8290
Uniprot ID
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Q16695
Background
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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H3K9me3; H3 histone; HIST1H3A; Histone cluster 1; H3a