Anti-Transcription Factor E3 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
TFE3
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R08-4W6
Isotype
-
IgG
Reactivity
Application
Application Details
-
IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
Immunogen
-
A synthesized peptide derived from human TFE3
Molecular Weight
-
-
Formulation
-
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
-
Liquid
Gene ID
-
7030
Uniprot ID
-
P19532
Background
-
Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity.
Research Area
-
Immunology
Synonyms
-
TFE3; BHLHE33; Transcription factor E3; Class E basic helix-loop-helix protein 33; bHLHe33