Anti-TRAM2 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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TRAM2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R01-7F4
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthesized peptide derived from human TRAM2
Molecular Weight
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Calculated MW: 43 kDa; Observed MW: 43 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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9697
Uniprot ID
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Q15035
Background
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TRAM2 is necessary for collagen type I synthesis. May couple the activity of the ER Ca2+ pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca2+ concentration at the site of collagen synthesis, and a high Ca2+ concentration may be necessary for the function of molecular chaperones involved in collagen folding.
Research Area
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Signal Transduction
Synonyms
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KIAA0057; TRAM like protein; Tram2; Translocating chain associating membrane protein 2; Translocation associated membrane protein 2