Anti-TRAF6 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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TRAF6
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R05-2D6
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthetic peptide of human TRAF6
Molecular Weight
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Calculated MW: 60 kDa; Observed MW: 60 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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7189
Uniprot ID
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Q9Y4K3
Background
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TRAFs (TNF receptor-associated factors) are a family of multifunctional adaptor proteins that bind to surface receptors and recruit additional proteins to form multiprotein signaling complexes capable of promoting cellular responses. Members of the TRAF family share a common carboxy-terminal TRAF domain which mediates interactions with associated proteins; many also contain amino-terminal Zinc/RING finger motifs.
Research Area
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Cell Biology
Synonyms
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TRAF6; RNF85; TNF receptor-associated factor 6; E3 ubiquitin-protein ligase TRAF6; Interleukin-1 signal transducer; RING finger protein 85