Anti-Toll-Like Receptor 7 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
TLR7
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R02-8B8
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
-
A synthesized peptide derived from human TLR7
Molecular Weight
-
Calculated MW: 121 kDa; Observed MW: 140 kDa
Formulation
-
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
-
Liquid
Gene ID
-
51284
Uniprot ID
-
Q9NYK1
Background
-
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Research Area
-
Immunology
Synonyms
-
Toll-Like Receptor 7; PRO285; TLR 7; Tlr7; Toll like receptor 7; UNQ248