Anti-Toll-Like Receptor 5 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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TLR5
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R01-3A3
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthesized peptide derived from human TLR5
Molecular Weight
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Calculated MW: 98 kDa; Observed MW: 98 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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7100
Uniprot ID
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O60602
Background
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Six human homologs of the Drosophila Toll receptor were initially identified based on their sequence similarities and designated toll-like receptors (TLR). Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Research Area
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Immunology
Synonyms
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Toll-Like Receptor 5; SLEB1; TIL3; Tlr5; Toll like receptor 5 precursor