Anti-TLE1/2/3/4 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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TLE1/TLE2/TLE3/TLE4
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
Immunogen
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The antiserum was produced against synthesized peptide derived from the C-terminal region of human TLE1/TLE2/TLE3/TLE4.
Molecular Weight
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Calculated MW: 83 kDa; Observed MW: 90 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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7088/7089/7090/7091
Uniprot ID
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Q04724/Q04725/Q04726/Q04727
Background
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Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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similar to transducin-like enhancer of split 1/2/3/4