Anti-Tissue Type Plasminogen Activator Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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PLAT
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R05-3D2
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human PLAT
Molecular Weight
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Calculated MW: 63 kDa; Observed MW: 63 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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5327
Uniprot ID
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P00750
Background
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This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling.
Research Area
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Cardiovascular
Synonyms
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TPA; T-PA; TPA1; PLAT; Tissue plasminogen activator