Anti-Thrombomodulin Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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Thbd
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R02-1G1
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Recombinant protein of mouse Thrombomodulin
Molecular Weight
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Calculated MW: 62 kDa; Observed MW: 95 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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21824
Uniprot ID
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P15306
Background
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Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
Research Area
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Cardiovascular
Synonyms
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CD141; Fetomodulin; THBD; THRM; thrombomodulin; TM