Anti-Thioredoxin Interacting Protein Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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TXNIP
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human TXNIP
Molecular Weight
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Calculated MW: 44 kDa; Observed MW: 53 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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10628
Uniprot ID
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Q9H3M7
Background
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May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm.
Research Area
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Signal Transduction
Synonyms
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HHCPA78; THIF; TXNIP; VDUP1