Anti-TCEA1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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TCEA1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R07-9E4
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Recombinant protein of human TCEA1
Molecular Weight
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Calculated MW: 34 kDa; Observed MW: 34 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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6917
Uniprot ID
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P23193
Background
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Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.MiscellaneousS-II binds to RNA-polymerase II in the absence of transcription.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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SII; TCEA; TF2S; GTF2S; TFIIS