Anti-TATA Box Binding Protein (9D1) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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TBP
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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9D1-5D6-3A2
Isotype
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IgG1
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Purified recombinant protein expressed in E.coli.
Molecular Weight
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Calculated MW: 38 kDa; Observed MW: 35-45 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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6908
Uniprot ID
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P20226
Background
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As one of the few proteins in the preinitation complex that binds DNA in a sequence-specific manner, it helps position RNA polymerase II over the transcription start site of the gene. However, it is estimated that only 10-20% of human promoters have TATA boxes. Therefore, TBP is probably not the only protein involved in positioning RNA polymerase II. This protein is not suitable for samples where the nuclear envelope has been removed.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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TBP; GTF2D1; TF2D; TFIID; TATA-box-binding protein; TATA sequence-binding protein; TATA-binding factor; TATA-box factor; Transcription initiation factor TFIID TBP subunit