Anti-TARC/CCL17 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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CCL17
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R05-8X-7
Isotype
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IgG
Reactivity
Application
Application Details
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IHC: 1/100-1/200
Immunogen
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Recombinant protein of human TARC
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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6361
Uniprot ID
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Q92583
Background
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This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.
Research Area
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Immunology
Synonyms
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TARC; CCL17; SCYA17; C-C motif chemokine 17;C-C motif chemokine 17;Small-inducible cytokine A17;Thymus and activation-regulated chemokine