Anti-SynGAP Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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SYNGAP1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human SynGAP
Molecular Weight
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Calculated MW: 148 kDa; Observed MW: 148 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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8831
Uniprot ID
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Q96PV0
Background
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Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity.
Research Area
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Neuroscience
Synonyms
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MRD5; p135 SynGAP; RASA1; RASA5; SYNGAP1