Anti-Survivin (8B9) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
BIRC5
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
8B9-6G6-1G4
Isotype
-
IgG1
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
-
Recombinant Protein of Survivin
Molecular Weight
-
Calculated MW: 16 kDa; Observed MW: 16 kDa
Formulation
-
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
-
Liquid
Gene ID
-
332
Uniprot ID
-
O15392
Background
-
Survivin is an apoptosis inhibitor that is expressed during the G2/M phase of the cell cycle. Associates with the microtubules of the mitotic spindle and any disruption results in the loss of apoptosis activity. May play a role in neoplasia.
Research Area
-
Cell Biology
Synonyms
-
BIRC5; API4; IAP4; Baculoviral IAP repeat-containing protein 5; Apoptosis inhibitor 4; Apoptosis inhibitor survivin