Anti-Stromal Interaction Molecule 1 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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STIM1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Immunogen
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A synthesized peptide derived from human Stromal interaction molecule 1
Molecular Weight
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Calculated MW: 77 kDa; Observed MW: 77 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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6786
Uniprot ID
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Q13586
Background
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STIM1 is a potential tumor suppressor; defects in STIM1 may cause rhabdomyosarcoma and rhabdoid tumors. STIM1 can either homodimerize or form heterodimers with STIM2. STIM2 possesses a high sequence identity to STIM1 and can function as an inhibitor of STIM1-mediated plasma membrane store-operated Ca2+ entry. However, further investigation is required to elucidate the true physiological function of STIM2.
Research Area
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Neuroscience
Synonyms
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GOK; TAM; TAM1; IMD10; STRMK; D11S4896E