Anti-Stromal Interaction Molecule 1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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STIM1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R07-9F9
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthetic peptide of human Stromal interaction molecule 1
Molecular Weight
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Calculated MW: 77 kDa; Observed MW: 77 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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6786
Uniprot ID
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Q13586
Background
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STIM1 is a potential tumor suppressor; defects in STIM1 may cause rhabdomyosarcoma and rhabdoid tumors. STIM1 can either homodimerize or form heterodimers with STIM2. STIM2 possesses a high sequence identity to STIM1 and can function as an inhibitor of STIM1-mediated plasma membrane store-operated Ca2+ entry. However, further investigation is required to elucidate the true physiological function of STIM2.
Research Area
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Neuroscience
Synonyms
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GOK; TAM; TAM1; IMD10; STRMK; D11S4896E