Anti-STRAP Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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STRAP
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Full length fusion protein
Molecular Weight
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Calculated MW: 38 kDa; Observed MW: 38 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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11171
Uniprot ID
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Q9Y3F4
Background
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Serine-threonine kinase receptor-associated protein is an enzyme that in humans is encoded by the STRAPgene. The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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MAWD; PT-WD; UNRIP