Anti-STAT5 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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STAT5A/STAT5B
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/50 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human STAT5A/B
Molecular Weight
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Calculated MW: 90 kDa; Observed MW: 90 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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6776/6777
Uniprot ID
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P42229/P51692
Background
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Stat5 is activated in response to a wide variety of ligands including IL-2, GM-CSF, growth hormone and prolactin. Phosphorylation at Tyr694 is obligatory for Stat5 activation. This phosphorylation is mediated by Src upon erythropoietin stimulation. Stat5 is constitutively active in some leukemic cell types.
Research Area
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Signal Transduction
Synonyms
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Mammary gland factor (STAT5A); Signal transducer and activator of transcription 5A; Stat 5a; STAT 5b; STAT5A; Transcription factor STAT5B