Anti-SRRT Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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SRRT
Host
Storage
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Store at 2-8°C for up to 2 weeks. store at -20°C for long term storage in small aliquots. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/2000
Immunogen
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This DANRE srrt antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide from DANRE srrt.
Molecular Weight
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Calculated MW:103 kDa; Observed MW: 103 kDa
Formulation
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Liquid in PBS containing 0.09% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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192311
Uniprot ID
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Q66I22
Background
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Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs (By similarity). Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity).
Research Area
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Signal Transduction
Synonyms
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Serrate RNA effector molecule homolog, Arsenite-resistance protein 2, srrt, ars2