Anti-SPINK5 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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SPINK5
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R06-6C1
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthetic peptide of human SPINK5
Molecular Weight
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Calculated MW: 121 kDa; Observed MW: 121 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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11005
Uniprot ID
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Q9NQ38
Background
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Serine protease inhibitor, probably important for the anti-inflammatory and/or antimicrobial protection of mucous epithelia. Contribute to the integrity and protective barrier function of the skin by regulating the activity of defense-activating and desquamation-involved proteases. Inhibits KLK5, it's major target, in a pH-dependent manner. Inhibits KLK7, KLK14 CASP14, and trypsin.
Research Area
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Cell Biology
Synonyms
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NS; NETS; LEKTI; LETKI; VAKTI