Anti-SPHK1 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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SPHK1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human SPHK1
Molecular Weight
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Calculated MW: 43 kDa; Observed MW: 51 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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8877
Uniprot ID
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Q9NYA1
Background
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Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra-and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol.
Research Area
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Signal Transduction
Synonyms
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SK1; Sphingosine kinase 1; SPHK; Sphk1; SPK