Anti-SOX10 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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SOX10
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R09-7Y-6
Isotype
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IgG
Reactivity
Application
Application Details
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WB:1/500-1/1000,IHC-P:1/50-1/100,ICC/IF:1/50
Immunogen
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Peptide
Molecular Weight
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Calculated MW: 49 kDa; Observed MW:60-80 kDa
Formulation
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Liquid in PBS, Glycerol and BSA
Form
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Liquid
Gene ID
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6663
Uniprot ID
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P56693
Background
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Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3. Transcriptional activator of MBP, via binding to the gene promoter.
Research Area
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Cell Biology
Synonyms
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–