Anti-SOX1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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SOX1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R05-9W-1
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100
Immunogen
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Peptide
Molecular Weight
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Calculated MW:39 kDa;Observed MW: 39 kDa
Formulation
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Liquid in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Form
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Liquid
Gene ID
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6656
Uniprot ID
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O00570
Background
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Sox (Sry-related box) genes encode a family of transcription factors that play a myriad of roles in developmental processes. Sox1 and Sox2 are the earliest markers that identify neuroectodermal tissue, and these markers, together with Sox9 collectively mark neuronal stem cells (NSC's) that are present in neurogenically active areas of the mature rodent brain. Sox1 is thought to maintain the cell cycle and promote self renewal in NSCs.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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Sex determining region Y box 1; sox1; SRY; SRY box containing gene 1; SRY related HMG box gene 1; Transcription factor Sox-1