Anti-SMCHD1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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SMCHD1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R01-7N6
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human SMCHD1
Molecular Weight
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Calculated MW: 226 kDa; Observed MW: 226 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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23347
Uniprot ID
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A6NHR9
Background
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Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the methyltransferase DNMT3B (By similarity). Required for DUX4 silencing in somatic cells.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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BAMS; FSHD2; Smchd1