Anti-Smad1 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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SMAD1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Immunogen
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This SMAD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide from the Central region of human SMAD1.
Molecular Weight
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Calculated MW: 52 kDa; Observed MW: 65 kDa
Formulation
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Liquid in PBS containing 0.09% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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4086
Uniprot ID
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Q15797
Background
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Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
Research Area
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Signal Transduction
Synonyms
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SMAD1; BSP1; MADH1; MADR1; Mothers against decapentaplegic homolog 1; MAD homolog 1; Mothers against DPP homolog 1; JV4-1; Mad-related protein 1; SMAD family member 1; SMAD 1; Smad1; hSMAD1; Transforming growth factor-beta-signaling protein